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Table 3 Changes in baseline BP measurements for non-responders at the end of therapy

From: Antihypertensive efficacy of metoprolol XL/Low dose chlorthalidone (6.25 mg) combination: a randomized, comparative study in Indian patients with mild-to-moderate essential hypertension

Efficacy Parameters Metoprolol XL + Chlorthalidone
(n = 30)
Metoprolol XL + HCTZ
(n = 30)
P value
Mean SBP (mmHg) (At 4 weeks) 139.23 ± 10.40 (120.0-160.0) 141.40 ± 13.29 (116.0-172.0) 0.485
Mean SBP (mmHg) (At 12 weeks) 127.40 ± 12.54 (106.0-134.0) 133.57 ± 13.76 (100.0-164.0) 0.075
Mean DBP (mmHg) (At 4 weeks) 87.57 ± 7.94 (70.0-96.0) 89.57 ± 6.37 (80.0-98.0) 0.287
Mean DBP (mmHg) (At 12 weeks) 81.80 ± 7.61 (70.0-88.0) 85.43 ± 8.01 (70.0-104.0) 0.077
Mean Fall in SBP (mmHg) -11.8 ± 13.8 -7.8 ± 14.4 0.277
Mean Fall in DBP (mmHg) -5.8 ± 10.7 -4.13 ± 7.98 0.507
Responders 25 19 0.045
Non-responders 5 11