Effects of exercise training on mobilization and functional activity of blood-derived progenitor cells in patients with acute myocardial infarction

Table 2 Response to exercise training and traditionaly rehabilitation in patients with STEMI evaluated by ergometry, exercise echogardiography, exercise spiroergometry and BNP (brain natriuretic peptide)

Clinical status	t₀	t₁	p⁺	t₂	p^#	p^§
NYHA-classification
exercise training	2.64 ± 0.57	1.32 ± 0.4 8	< 0.001	1.52 ± 0.51	0.096	< 0.001
Controls	2.75 ± 0.62	2.25 ± 0.6 2	0.083	2.42 ± 0.52	n.s.	n.s.
p	n.s.	< 0.001		< 0.001
BNP, pg/ml
exercise train ing	121 ± 94	75 ± 47	< 0.001	54 ± 42	< 0.0 01	< 0.001
controls	127 ± 78	111 ± 80	n.s.	92 ± 63	n.s.	n.s.
p	n.s.	n.s.		0.080
Ergometry
max. workload, watt
exercise train ing	101 ± 33	137 ± 53	< 0.001
controls	-	-
p	-	-
Duration of exercise, min
exercise train ing	5.68 ± 2.03	7.18	0.007
controls	-	-
p	-	-
Exercise echocardiography
EF at rest, %
exercise train ing	46 ± 12	49 ± 12	0.028	49 ± 11	n.s.	0.0 09
controls	48 ± 13	49 ± 16	n.s.	49 ± 12	n.s.	n.s.
p	n.s.	n.s.		n.s.
EF at peak exercise, %
exercise train ing	57 ± 14	60 ± 14	0.031	60 ± 15	n.s.	0.0 20
controls	57 ± 6	58 ± 7	n.s.	59 ± 8	n.s.	n.s.
p	n.s.	n.s.		n.s.
Exercise spiroergometry
max. workload, watt
exercise train ing	123 ± 47	140 ± 53	0.004	137 ± 52	n.s.	0.0 11
controls	125 ± 33	122 ± 41	n.s.	131 ± 44	n.s.	n.s.
p	n.s.	n.s.		n.s.
VO ₂ max, ml/min
exercise train ing	1641 ± 522	1842 ± 724	0.017	1855 ± 695	n.s.	0.0 12
controls	1389 ± 547	1439 ± 465	n.s.	1851 ± 429	0.050	n.s.
p	n.s.	n.s.		n.s.
VO ₂ max/kg, ml/min/kg
exercise train ing	20.0 ± 4.3	22.5 ± 6.5	0.015	22.9 ± 6.6	n.s.	0.0 12
controls	17.6 ± 5.6	17.3 ± 4.5	n.s.	21.7 ± 5.0	0.093	n.s.
p	n.s.	0.096		n.s.

EF = left ventriculare ejection fraction; VO₂max = maximum oxygen consumption; BNP = brain natriuretic peptide; Values are mean ± SD. p⁺ = t₀ vs. t₁ ; p^# = t₁ vs. t₂; p^§ = t₀ vs. t₂