Relative content of cytosolic and nuclear FKBP51 protein and FKBP51 mRNA in cells isolated from induced sputum of stable COPD patients treated with formoterol + budesonide (F/ICS; n = 18) and formoterol + budesonide + theophylline (F/ICS/Th; n = 18) b.i.d. for 4 wk. Expressions of FKBP51 were equalized in each sample for loading and numerized with density software. The mean FKBP51 expression in cytosolic fraction of cells isolated from F/ICS-treated patients was set as 100 relative units. *P < 0.05 compared with the F/ICS-treated group; **P < 0.01 compared with the F/ICS-treated group.