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Table 4 Case-control analysis of ADAM33 F+1 allele frequencies and genotype distributions (genotypes in comparison with controls)

From: ADAM33 gene polymorphisms in chronic obstructive pulmonary disease

  All COPD Stable COPD Unstable COPD Control
Homozygotes for wild type 53
(35.3%)
24
(40.0%)
29
(32.2%)
61
(40.1%)
Heterozygotes for mutation 73
(48.7%)
30
(50.0%)
43
(47.8%)
74
(48.7%)
Homozygotes for mutation 24
(16.0%)
6
(10.0%)
18
(20.0%)
17
(11.2%)
Carrier frequency of the mutant allele 40.3%
(121/300)
35.0%
(42/120)
43.9%
(79/180)
35.5%
(180/304)
P-value (Armitage's trend test) 0.22 0.92 0.07