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Table 2 Test performance evaluation of plasma DNA quantification by real-time qPCR.

From: Real-time PCR quantification of plasma DNA in non-small cell lung cancer patients and healthy controls

Cut-off

Sensitivity

95% CI

Specificity

95% CI

+LR

-LR

≥ 0.91

100

76.7-100.0

0

0.0-20.8

1.00

 

≥ 1.98

92.9

66.1-98.8

62.5

35.5-84.7

2.48

0.11

≥ 2.78*

85.7

57.2-97.8

75.0

47.6-92.6

3.43

0.19

≥ 3.36

78.6

49.2-95.1

81.3

54.3-95.7

4.19

0.26

≥ 5.39

64.3

35.2-87.1

87.5

61.6-98.1

5.14

0.41

≥ 7

50

23.1-76.9

100

79.2-100.0

 

0.50

  1. *The cut-off value corresponding with the highest average of sensitivity and specificity. +LR is a positive and -LR is a negative likelihood ratio.
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European Journal of Medical Research

ISSN: 2047-783X

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