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Table 2 Test performance evaluation of plasma DNA quantification by real-time qPCR.

From: Real-time PCR quantification of plasma DNA in non-small cell lung cancer patients and healthy controls

Cut-off Sensitivity 95% CI Specificity 95% CI +LR -LR
≥ 0.91 100 76.7-100.0 0 0.0-20.8 1.00  
≥ 1.98 92.9 66.1-98.8 62.5 35.5-84.7 2.48 0.11
≥ 2.78* 85.7 57.2-97.8 75.0 47.6-92.6 3.43 0.19
≥ 3.36 78.6 49.2-95.1 81.3 54.3-95.7 4.19 0.26
≥ 5.39 64.3 35.2-87.1 87.5 61.6-98.1 5.14 0.41
≥ 7 50 23.1-76.9 100 79.2-100.0   0.50
  1. *The cut-off value corresponding with the highest average of sensitivity and specificity. +LR is a positive and -LR is a negative likelihood ratio.