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Table 1 Effects of neoadjuvant therapy and subsequent surgery on the serum concentration of evaluated tumor markers.

From: Neoadjuvant therapy affects tumor growth markers in early stage non-small-cell lung cancer

 

Before neoadjuvant therapy

After neoadjuvant therapy

After surgery

TGF-β (ng/ml)

20888 ± 6059

15769 ± 6428

P = 0.044

14503 ± 5219

P = 0.007

VEGF (pg/ml)

414 ± 191

326 ± 236

636 ± 409

P = 0.001

sAPO-1 (pg/ml)

4.2 ± 1.4

3.7 ± 1.5

4.1 ± 2.4

TIMP (pg/ml)

543 ± 87

509 ± 131

563 ± 124

  1. Data are means ± SD. Kruskal-Wallis analysis of variance was applied to test for statistical significance.