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Table 1 Effects of neoadjuvant therapy and subsequent surgery on the serum concentration of evaluated tumor markers.

From: Neoadjuvant therapy affects tumor growth markers in early stage non-small-cell lung cancer

  Before neoadjuvant therapy After neoadjuvant therapy After surgery
TGF-β (ng/ml) 20888 ± 6059 15769 ± 6428
P = 0.044
14503 ± 5219
P = 0.007
VEGF (pg/ml) 414 ± 191 326 ± 236 636 ± 409
P = 0.001
sAPO-1 (pg/ml) 4.2 ± 1.4 3.7 ± 1.5 4.1 ± 2.4
TIMP (pg/ml) 543 ± 87 509 ± 131 563 ± 124
  1. Data are means ± SD. Kruskal-Wallis analysis of variance was applied to test for statistical significance.