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Table 2 Peripheral blood lymphocyte subsets in patients with systemic sclerosis (SSc) and healthy controls

From: Absolute count of T and B lymphocyte subsets is decreased in systemic sclerosis

Lymphocytes

SSc (n = 29)

Controls (n = 29)

P-value

Lymphocytes/μl

1676 ± 602

2273 ± 561

0.0042*

CD3+

   

absolute/μl

1193 ± 474

1688 ± 424

0.0014*

percentage (%)

71 ± 7

74 ± 5

0.419

CD4+

   

absolute/μl

808 ± 279

1115 ± 346

0.0070*

percentage (%)

49 ± 9

49 ± 8

0.747

CD4+/CD8+ ratio

2.3 ± 1.2

2.8 ± 1.6

0.165

CD8+

   

absolute/μl

363 ± 256

570 ± 214

0.021*

percentage (%)

21 ± 7

25 ± 8

0.582

CD19+

   

absolute/μl

197 ± 89

297 ± 136

0.024*

percentage (%)

12 ± 5

13 ± 4

0.725

CD56+

   

absolute/μl

265 ± 153

247 ± 114

0.632

percentage (%)

16 ± 8

11 ± 4

0.0588

  1. *, statistically significant according to independent t-test and Bonferroni-correction