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Table 3 Primary target values and parameter settings (absolute numbers and percent (%) in parenthesis)

From: Delivery room management of very low birth weight infants in Germany, Austria and Switzerland - a comparison of protocols

 

Germany

Austria

Switzerland

All countries

Differences between countries

 

N = 153

N = 11

N = 26

N = 190

p-value

Oxygen therapy

     

FiO2

     

   0.21

47/147 (32)

1/11 (9)

8/25 (32)

56/183 (31)

 

   0.22 - 0.5

81/147 (55)

10/11 (91)

14/25 (56)

105/183 (57)

0.241

   0.51 - 1.0

19/147 (13)

0/11 (0)

3/25 (12)

3/183 (12)

 

Target SpO2

     

   < 85%

21/145 (14)

1/7 (14)

8/24 (33)

30/176 (17)

 

   85-90%

108/145 (74)

5/7 (71)

13/24 (54)

126/176 (72)

0.231

   > 90%

16/145 (11)

1/7 (14)

3/24 (13)

20/176 (11)

 

High FiO2, taper down

31/152 (20)

2/11 (18)

2/25 (20)

38/188 (20)

 

Low FiO2, taper up

12/152 (80)

9/11 (82)

20/25 (80)

150/188 (80)

0.984

Non-invasive respiratory support

     

Prolonged inflations

41/148 (28)

3/11 (27)

3/25 (12)

47/184 (26)

0.248

   > 5 sec

     

Starting CPAP

     

   ≤ 3 cmH20

9/149 (6)

0/0 (0)

1/21 (5)

10/180 (6)

 

   4-5 cmH20

114/149 (77)

6/10 (60)

19/21 (90)

139/180 (77)

0.170

   > 5 cmH20

26/149 (17)

4/10 (40)

1/21 (5)

31/180 (17)

 

Invasive respiratory support

     

INSURE yes

43/142 (30)

4/9 (44)

4/19 (21)

51/170 (30)

0.444

Surfactant

     

   100 mg/kg

129/145 (89)

3/7 (43)

11/14 (79)

143/166 (86)

0.002

   150-200 mg/kg

16/145 (11)

4/7 (57)

3/14 (21)

23/166 (14)

 
  1. FiO2 = fraction of inspired oxygen
  2. CPAP = continuous positive airway pressure
  3. INSURE = intubate, surfactant application, extubate immediately
  4. SpO2 = peripheral saturation of oxygen