Table 1 Cost-effectiveness of antibiotic treatment strategies in the management of MRB infections

Early adequate first-line antibiotic therapy

Shorter duration of therapy

Early transfer from ICU to normal ward

Shorter LOS

Less complications

[9–13]

IV-to-oral switch

Shorter i.v. therapy

Earlier discharge and outpatient treatment

[14–17]

Adjusted duration of therapy

Less adverse events

Less selection of resistance

Less drug cost

Shorter LOS

[18–22]

Adherence to guidelines

Shorter duration of therapy

Shorter LOS

Less complications

Less ICU admissions

Less HMV

[7, 24, 25]