Effect of intracerebroventricular injection of interleukin-1-beta on the ventilatory response to hyperoxic hypercapnia

Table 1 Breathing pattern before and after intracerebroventricular injections of IL-1β.

Variables	Interleukin-1β
	Before	After
Minute ventilation, ml/min	103.0 ± 5.3	126.0 ± 3.8**
Tidal volume, ml	1.0 ± 0.1	1.2 ± 0.1
Respiratory frequency, breaths/min	112.0 ± 7.0	113.0 ± 7.0
Mean inspiratory flow, ml/s	3.7 ± 0.3	4.4 ± 0.1*
Eesophageal pressure, mmH₂O	1.6 ± 0.4	2.5 ± 0.5
End-tidal CO₂, mmHg	34.0 ± 3.0	30.0 ± 3.0

Values are means ± SE. *P < 0.05 and **P < 0.01 for the comparison before and IL-1β treatment.

ISSN: 2047-783X