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Table 2 Comparison of clinical and immunological parameters between healthy adults in Burkina Faso and Germany

From: Constitutive activation and accelerated maturation of peripheral blood t cells in healthy adults in burkina faso compared to Germany: The case of malaria?

  Germany Burkina Faso p
n = 20 40  
Female [n = ] 13 (65%) 18 (45%) -
Age [median, range] 28 (23-38) 27 (19-37) 0.68
Naive CD4 + lymphocytes    
CD45bright CCR7+ [% of CD4+ lymphocytes] 38 (16-60) 22 (3-48) < 0.0001
CD4 + T-cell activation    
CD95+ [% of CD4+ T-cells J 72 (57-100) 84 (50-97) 0.002
CD95-ABC of CD4+CD95dimT-cells [AUJ 108 (65-619) 26.3 (196-686) < 0.0001
CD95-ABC of CD4+CD95brightT-cells [AUJ 2996 (1655-5331) 3316 (1474-5285) 0.05
Naïve CD8 + lymphocytes    
CD45bright CCR7+ [% of CD8+ lymphocytes] 26 (6-53) 23 (5-52) 0.56
CD8 + T-cell activation    
CD38+ [% of CD8+ T-cells] 67 (56-97) 77 (35-99) 0.03
CD38-ABC of CD8+CD38+T-cells [AU] 1384 (440-3270) 1560 (866-2450) 0.33
  1. If not otherwise indicated, median values with 10th and 90th percentiles in parentheses are shown. The Mann-Whitney U-test was used to compare groups. Abbreviations: ABC = Antibody binding capacity, AU = arbitrary units.