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Table 1 Antimicrobial susceptibilities of 6 epidemic Burkholderia cepacia complex isolates (P-5, P-6, P-7. P-8. and P-9) in the NICU and 2 isolates (P-a and P-B) from unrelated wards with the neg combo 3.12J panels with the MicroScan Walkaway 40 System

From: Successful cessation of transmitting healthcare-associated infections due to Burkholderia cepacia complex in a neonatal intensive care unit in a Japanese children's hospital

Patient No.#

Date of Isolation day/month/year

Specimen Obtained

MIC(μg/ml)

 

PIPC

CAZ

CFS

CFPM

CZOP

AZT

IPM

MEPM

TOB

AMK

GM

MINO

LVFX

CPFX

ST

FOM

C/S

P/T

P-A

07/09/2010

bronchial aspirate

> 64

> 16

> 16

> 16

> 16

> 16

> 8

< 1

> 8

> 32

> 8

< 2

2

2

< 2

> 16

> 32

< 8

P-B

13/09/2010

salivary fluid

64

4

> 16

> 16

> 16

> 16

> 8

2

> 8

> 32

> 8

4

4

> 2

> 2

> 16

> 32

< 8

P-5

14/09/2010

bronchial aspirate

> 64

4

> 16

> 16

> 16

> 16

> 8

< 1

> 8

> 32

> 8

< 2

1

1

< 2

> 16

> 32

< 8

P-6a

21/09/2010

peripheral blood

> 64

4

> 16

> 16

> 16

> 16

8

< 1

> 8

> 32

> 8

< 2

1

1

< 2

> 16

> 32

< 8

P-6b

12/10/2010

catheterized urine

> 64

8

> 16

> 16

> 16

> 16

8

< 1

> 8

> 32

> 8

< 2

1

1

< 2

> 16

> 32

< 8

P-7

14/09/2010

bronchial aspirate

64

8

> 16

> 16

> 16

> 16

> 8

< 1

> 8

> 32

> 8

< 2

1

1

< 2

> 16

> 32

< 8

P-8

28/09/2010

bronchial aspirate

> 64

4

> 16

> 16

> 16

> 16

8

< 1

> 8

> 32

> 8

< 2

1

1

< 2

> 16

> 32

< 8

P-9

18/01/2011

bronchial aspirate

64

8

> 16

> 16

> 16

> 16

8

< 1

> 8

> 32

> 8

< 2

< 0.5

0.5

< 2

> 16

> 32

< 8

  1. PIPC: piperacillin, CAZ: ceftazidime, CFS: cefsulodin, CFPM: cefepime, CZOP: cefozopran, AZT: aztreonam, IPM: imipenem, MEPM: meropenem, TOB: tobramycin AMK: amikacin, GM: gentamicin, MINO: minocycline, LVFX: levofloxacin,, CPFX: ciprofloxacin, ST: sulfamethoxazole/trimethoprim, FOM: fosfomycin, C/S: cefoperazone/sulbactam, P/T: piperacillin/tazobactam #: P-A: Patient a, P-B: Patient B, both hospitalized in different wards unrelated to the NICU. as for P-5, -6, -7, -8, and -9, see text in the Results section, for the backgrounds of the isolates.