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Table 1 Baseline characteristics of healthy controls (n = 40) and patients with NASH without (n = 50) and with vitamin supplementation (n = 7)

From: Plasma levels of vitamin E and carotenoids are decreased in patients with nonalcoholic steatohepatitis (NASH)

 

Healthy controls

(n = 40)

NASH

(n = 50)

P value (different from control)

NASH + vitamin supplements

(n = 7)

P-value (different from NASH)

α-Tocopherol [nmol/ml]

26.8 ± 7.9

22.4± 8.1

0.01

39.6 ± 1.5

0.0001

γ-Tocopherol [nmol/ml]

2.5 ± 0.8

2.5 ± 0.9

n.s.

3.0 ± 1.0

n.s.

Retinol [nmol/ml]

1.5 ± 1.9

1.2 ± 0.5

n.s.

1.3 ± 0.4

n.s.

Lutein [nmol/ml]

0.33 ± 0.11

0.19 ± 0.09

0.0001

0.26 ± 0.17

n.s.

Zeaxanthin [nmol/ml]

0.08 ± 0.03

0.04 ± 0.01

0.0001

0.045 ± 0.03

n.s.

Cryptoxanthin [nmol/ml]

0.13 ± 0.07

0.09 ± 0.09

n.s. (0.06)

0.12 ± 0.06

n.s.

Lycopene [nmol/ml]

0.42 ± 0.24

0.15 ± 0.16

0.001

0.50 ± 0.37

n.s. (0.07)

α-Carotene [nmol/ml]

0.06 ± 0.05

0.03 ± 0.03

0.005

0.07 ± 0.09

n.s.

β-Carotene [nmol/ml]

0.39 ± 0.26

0.25 ± 0.26

0.01

0.42 ± 0.27

0.03

Ferritin [μg/l]

96 ± 73

237 ± 293

0.007

103 ± 99

n.s.

Ts [%]

31 ± 13

34 ± 13

n.s.

34 ± 11

n.s.

Age [years]

50 ± 15

51 ± 16

n.s.

49 ± 10

n.s.

Gender [% males]

54

55

n.s.

57

n.s.

  1. Abbr.: TS -- transferrin saturation