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Table 1 Baseline demographic and clinical characteristics of patients starting a new PI-based cART regimen

From: Changes in lipid profiles after switching to a protease inhibitor-containing cART - unfavourable effect of fosamprenavir in obese patients

   Starting therapy with ATV/r FPV/r SQV/r pa
Characteristic       
Number of patients   N 84 23 17  
DEMOGRAPHIC CHARACTERISTICS       
Male patients   n (%) 62 (74) 18 (78) 14 (82) 0.72
Age (years)   Median 43 44 41 0.69
   (IQRb) (37; 54) (38; 50) (35; 50)  
Caucasian patients   n (%) 66 (79) 21 (91) 14 (82) 0.71
HIV risk category MSM c n (%) 41 (49) 14 (61) 12 (70)  
  heterosexual n (%) 17 (20) 4 (17) 2 (12) 0.76
  Other n (%) 26 (31) 5 (22) 3 (18)  
HIV DISEASE CHARACTERISTICS       
Duration of known HIV infection (years)   Median 8.8 10.5 8.8 0.41
   (IQR) (5.4; 12.8) (6.3; 15.3) (4.7; 10.5)  
Previous AIDS   n (%) 34 (40) 8 (35) 9 (53) 0.53
CD4 cell count (cells/μl blood)   Median 343 320 262 0.59
   (IQR) (221; 496) (138; 595) (81; 551)  
Patients with undetectable viral load d   n (%) 37 (44) 8 (35) 6 (35) 0.73
ANTIRETROVIRAL THERAPY       
Previous cART exposure   n (%) 79 (94) 20 (87) 16 (94) 0.50
Previous PI exposure   n (%) 55 (66) 15 (65) 14 (82) 0.40
Cumulative cART exposure (years)   Median 6,9 7,3 5,2 0.30
   (IQR) (3.2; 8.7) (3.8; 9.6) (3.5; 8.7)  
previous cART no cART n (%) 15 (18) 8 (35) 1 (6) 0.35
  other PI n (%) 40 (48) 11 (48) 10 (59) 0.69
  NRTI and/or NNRTI only n (%) 29 (35) 4 (17) 6 (35) 0.12
CARDIOVASCULAR RISK FACTORS       
BMI   Median 23,7 23,6 21,5 0.50
   (IQR) (21.3; 25.4) (20.5; 25.1) (19.3; 23.2)  
Current smoker   n (%) 39 (46) 9 (39) 6 (35) 0.23
Arterial hypertension e   n (%) 35 (42) 11 (48) 6 (35) 0.73
Diabetes mellitus   n (%) 7 (8) 1 (4) 0 (0) 0.40
Current lipid-lowering therapy   n (%) 5 (6) 2 (9) 2 (12) 0.67
  1. a: Kruskal-Wallis-H-test for metric variables, Chi2 -test for categorical variables; p-value for inter-group comparisons
  2. b: inter quartile range
  3. c: Men having sex with men
  4. d: less than 50 copies per ml of plasma
  5. e: diastolic blood pressure ≥90mmHg and/or systolic blood pressure ≥140mmHg or antihypertensive medication