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Table 5 Effect of current CD4 cell-count on the incidence of cancer.

From: Cancer risk in HIV-infected individuals on HAART is largely attributed to oncogenic infections and state of immunocompetence

 

Parameter

IRR

95% CI

p-value

All cancer

CD4 [per 100 cells/μl]

0.66

0.57 - 0.76

< 0.001

 

HBV co-infection

2.15

1.10 - 4.20

0.024

 

Use of HAART

0.28

0.19 - 0.41

< 0.001

 

Age [per 10 years]

1.23

1.03 - 1.46

0.023

Infectious related cancer

CD4 [per 100 cells/μl]

0.54

0.46 - 0.65

< 0.001

 

HBV co-infection

1.99

1.02 - 3.90

0.045

 

Use of HAART

0.24

0.16 - 0.37

< 0.001

 

Age [per 10 years]

1.10

0.91 - 1.34

0.334

non-infectious related cancer

CD4 [per 100 cells/μl]

1.11

0.97 - 1.26

0.125

 

HBV co-infection

3.08

0.73 - 13.1

0.129

 

Use of HAART

0.42

0.17 - 1.06

0.065

 

Age [per 10 years]

1.99

1.52 - 2.61

< 0.001

  1. adjusted for presumed eligible confounders.
  2. IRR incidence rate ratio; CI confidence interval