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Table 3 Pharmacodynamic parameters of voriconazole.

From: Pharmacology and metabolism of voriconazole and posaconazole in the treatment of invasive aspergillosis-review of the literature

Parameter

Characteristics

Activity

Candida: fungistatic

Aspergillus: fungicidal

Time course of activity

Candida: time-dependent fungistatic

Aspergillus: time-dependent slowly

fungicidal

PAFE in vitro

Candida: no PAFE

Aspergillus: short PAFE

  1. PAFE, post-antifungal effect
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European Journal of Medical Research

ISSN: 2047-783X

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