Table 2 Frequencies of drug-related adverse events observed in patients receiving echinocandins [86]
Adverse reaction, % of patients | Anidulafungin | Caspofungin | Micafungin |
|---|---|---|---|
Phlebitis | < 1 | 3.5-25 | 1.6 |
Fever | < 1 | 4-40 | 1-14 |
Abdominal pain | < 2 | 3.6 | 1 |
Nausea / vomiting | 1 / < 1 | 1-6 / 2-4 | 2-7 / 1-5 |
Diarrhea | 3.1 | 3.6 | 1.6 |
Headache | 1.3 | 4-15 | 2-17 |
Rash / pruritus | 1 / <2 | 1-10 / < 2 | 1-12 / <1 |
Leukopenia | < 1 | 6.2 | 1.6 |
Neutropenia | 1 | 1.9 | 1.2 |
Thrombocytopenia | < 2 | 3.1 | < 1 |
Hypokalemia | 3-10 | 2-10 | 1.2 |
Liver function test abnormalities | 3-5 | 1-15 | 1-8 |