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Table 7 Antifungal susceptibilities of rare Candida bloodstream isolates [41].

From: Epidemiology and antifungal resistance in invasive candidiasis

Species No. of isolates Antifungal agent No. inhibited at MIC (μg/ml) of:
    0.007 0.015 0.03 0.06 0.12 0.25 0.5 1 2 4 8 16 b 32 64 c ≥128
C. lasitaniae 171 Amphotericina     3 18 74 66 7 1 0 1 1    
  171 Fluconazole      20 52 64 20 5 3 1 1 3 2  
  171 Posaconazole 2 25 63 58 15 4 1 3        
  171 Voriconazole 123 33 3 4 2 3 2 1        
  96 Anidulafungin     5 13 36 40 2        
  166 Caspofungin   1 4 6 68 66 17 3 0 1      
  80 Micafungin 1 0 4 8 44 21 1 1        
C. guilliermondii 174 Amphotericin 1 0 1 8 63 62 24 6 2 1 1 0 0 5  
  175 Fluconazole       1 4 4 69 68 13 7 2 3 4
  175 Posaconazole   1 9 10 44 73 25 3 4 0 0 6    
  175 Voriconazole 2 11 19 83 43 8 1 0 2 0 0 6    
  107 Anidulafungin   1   2 6 5 7 37 41 8      
  156 Caspofungin    2 9 21 33 58 21 4 2 2 4    
  96 Micafungin   3 1 4 10 13 33 27 4 0 0 1    
C. orthopsilosis 102 Amphotericin       7 29 35 23 8      
  102 Fluconazole       6 28 45 9 8 4 1 0 1  
  102 Posaconazole   1 12 40 30 8 11         
  102 Voriconazole 1 24 40 24 1 10 1 1        
  52 Anidulafungin       3 12 28 9       
  91 Caspofungin 1 0 3 17 37 25 8         
  51 Micafungin      2 25 21 3        
C. kefyr 74 Amphotericin        20 43 10 0 0 0 0 1  
  74 Fluconazole      11 44 12 6 1       
  74 Posaconazole 1 3 17 21 23 8 1         
  74 Voriconazole 50 18 4 2            
  58 Anidulafungin   1 5 31 21           
  74 Caspofungin 11 56 6 1            
  53 Micafungin   4 2 26 1           
C. pelliculosa 40 Amphotericin      3 14 21 2        
  40 Fluconazole         2 7 24 7     
  40 Posaconazole     1 1 6 4 14 12 2      
  40 Voriconazole   1 1 1 21 13 3         
  14 Anidulafungin 2 9 2 1            
  37 Caspofungin 1 16 17 3            
  14 Micafungin   5 7 2            
C. famata 16 Amphotericin      1 6 8 0 0 1      
  16 Fluconazole         1 5 6 1 3    
  16 Posaconazole   2 0 0 1 5 7 1 2       
  16 Voriconazole    2 5 4 3 0 1 1       
  16 Anidulafungin     2 0 0 0 5 9       
  16 Caspofungin    1 2 2 5 3 2 1       
  16 Micafungin    1 1 0 2 5 5 2       
C. metapsilosis 30 Amphotericin      1 5 12 9 2 1      
  30 Fluconazole       1 0 19 9 1      
  30 Posaconazole   1 7 15 5 1 0 1        
  30 Voriconazole 1 4 22 2 1           
  11 Anidulafungin       5 3 2 1       
  24 Caspofungin    1 5 14 3 0 1        
  11 Micafungin       7 3 1        
C. dubliniensis 18 Amphotericin     1 8 7 1 1        
  18 Fluconazole      8 9 0 0 0 0 1     
  18 Posaconazole   4 6 7 1           
  18 Voriconazole 11 5 2             
  11 Anidulafungin    7 2 0 2          
  17 Caspofungin   2 6 9            
  9 Micafungin   4 3 2            
C. lipolytica 16 Amphotericin        1 5 5 4 1     
  16 Fluconazole        1 1 6 6 1 0 0 1  
  16 Posaconazole      2 1 8 4 0 1      
  16 Voriconazole   1 5 7 2 0 0 1        
  10 Anidulafungin       3 4 2 1       
  15 Caspofungin      6 9          
  10 Micafungin       6 3 1        
C. rugosa 16 Amphotericin        4 3 7 1 0 0 0 1  
  16 Fluconazole        1 0 4 3 2 4 1 1  
  16 Posaconazole     6 2 5 3         
  16 Voriconazole 2 1 4 3 1 3 2         
  16 Anidulafungin     3 1 4 3 3 0 0 2     
  16 Caspofungin    1 1 0 1 2 8 0 1 0 2    
  16 Micafungin    1 3 3 5 2 0 0 0 0 2    
  1. aAmphoiericin B MICs were determined by EtesL
  2. bFor posaconazole. voriconazole, anidulafungin. caspofungin. and micafungin. isolates for which MICs are reported to be 16 μg/ml encompass all isolates for which MICs were > 8 μg/ml.
  3. cFor amphotericin B. isolates for which the MIC is reported to be 64 μg/ml encompass all isolates for which MICs were > 32 μg/ml.