Dual endothelin-converting enzyme/neutral endopeptidase blockade in rats with D-galactosamine-induced liver failure

Table 3 Bivariate correlation between plasma endothelin-1 and markers of liver injury in all rats that received D-galactosamine (with and without SLV338 treatment)

	Endothelin-1
Aspartate aminotransferase	0.43**
Alanine aminotransferase	0.44**
Plasma glucose	-0.31*
Food intake within 48 h after GalN	-0.35*
Water intake within 48 h after GalN	-0.42**
Liver necrosis score	0.38*
Liver inflammation score	0.35*

GalN, D-galactosamine.
Pearson's correlation coefficient is given. Only statistically significant results are shown. There was no significant correlation between plasma big endothelin-1 and any markers of liver injury. n = 41. *p < 0.05, **p < 0.01.

ISSN: 2047-783X