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Table 2 Reported side effects (total number = 475)

From: Acceptance and tolerability of an adjuvanted nH1N1 vaccine in HIV-infected patients in the Cologne-Bonn cohort

  Occurrence Mean duration Mean severity Grade of Severity
     1 2 3 4
  N (%) Days (SD) (*) N (%) N (%) N (%) N (%)
        Local symptoms
Pain 285 (60%) 2.9 (± 1,1) 1.4 (± 0.5) 200 (42%) 69 (15%) 16 (3%) 0 (0%)
Swelling 95 (20%) 2.6 (± 1.3) 14.8 (± 17.1) †
Redness 52 (11%) 3.1 (± 1.5) 14.8 (± 17.1) †
        Systemic symptoms
Fever 47 (10%) 2.0 (± 1.0) 1.2 (± 0.3) 41 (9%) 6 (1%) 1 (0%) 0 (0%)
Muscle/jointache 172 (36%) 2.7 (± 1.3) 1.4 (± 0.5) 121 (25%) 38(8%) 14 (3%) 0 (0%)
Headache 126 (27%) 2.5 (± 1.5) 1.4 (± 0.6) 93 (20%) 21 (4%) 13 (3%) 0 (0%)
Fatigue 207 (44%) 2.8 (± 1.5) 1.5 (± 0.6) 125 (26%) 65 (14%) 20(4%) 0 (0%)
  1. SD Standard deviation
  2. (*) Severity: from 1 (mild) to 4 (life threatening), according to CTCAE v4.0 criteria (except severity of "swelling" and "redness", see below)
  3. † Severity of "swelling" and "redness": mean diameter (standard deviation) in millimeters
  4. ✤ no grading system was used