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Table 2 Differences between patients with rs12979860 C/T genotypes in the cross-sectional analysis.

From: Progression of liver fibrosis in HIV/HCV genotype 1 co-infected patients is related to the T allele of the rsI2979860 polymorphism of the IL28B gene

  CC CT TT P
Patients 42 (50%) 36 (43%) 6 (7%)  
Stiffness [kPa] 11.0 ± 8.6 13.2 ± 11.8 11.2 ± 11.9 n.s.
APRI score (median, range) 2.7 ± 7.1 (0.9; 0.3 - 43.2) 1.4 ± 1.2 (0.8; 0.4 - 5.7) 1.1 ± 0.6 (1.3; 0.5 - 1] n.s.
FIB-4 score (median, range) 3.8 ± 8.2 (1.6; 0.5 - 50,3) 2.2 ± 2.0 (1.5; 0.7 - 10.7) 2.2 ± 1.3 (1.6; 0.9 - 3.8) n.s.
ast [U/I] 65 ± 41 57 ± 33 64 ± 39 n.s.
ALT [U/l] 84 ± 52 74 ± 47 94 ± 87 n.s.
Thrombocytes [T/l] 163 ± 77 157 ± 5 181 ± 55 n.s.
HCV-load     n.s.
Undetectable: 9 (21%) 5 (14%)   
low (< 800000 IU/1) 6 (14%) 8 (23%)   
high (> 800000 1 U/1) 27 (64%) 22 (63°/.) 6 (100%)  
HCV-genotype     p = 0.03
1 20 (54%) 29 (88%) 3 (60%)  
2 5 (14%) 1 (3%)   
3 10(27%) 2 (6%) 1 (20%.)  
4 2 (5%) 1 (3%) 1 (20%)  
HAART 34(81%) 31(86%) 4(67%) n.s.
CD4 [cells/μl] (median, range) 428 (52 - 1757) 366 (10 - 966) 268 (85 - 1056)  
  428 (52 - 1757) 356 (10 - 1056) p = 0.02
< 50 HIV copies/ml 35 (83%) 23 (64%) 4 (67%) n.s.