Idiopathic recurrent calcium urolithiasis (IRCU): pathophysiology evaluated in light of oxidative metabolism, without and with variation of several biomarkers in fasting urine and plasma - a comparison of stone-free and -bearing male patients, emphasizing mineral, acid-base, blood pressure and protein status

Table 3 Ranking of frequency distribution of SF and SB patients upon stratification according to medians of parameters selected from Figure 1, Tables 2a, 2b, Appendix II

Parameters^n-1	N⁺	LOW*	SF	HIGH**	SF
			SB		SB
U-pH^a	154	5.42 (0.07)***	50	6.57	29	0.0007⁺⁺
		5.48 (0.07)	27	6.77	48	0.0006⁺⁺⁺
B-HCOj₃ ^{- b}	154	21.7(0.3)	33	25.3 (0.3)	46	0.036
		21.9 (0.2)	44	24.9(0.2)	31	0.026
D-BP^c	130	75 (0.9)	34	91 (2)	31	0.052
		69(1.5)	23	89(1)	42	0, 038
P-UA^d	154	307 (5)	45	412(10)	34	0.076
		307 (7)	32	403 (6)	43	0.053
P-N-Alb-P^e	154	20.1 (0.04)	34	27.1 (0.05)	45	0.108
		20.1 (0.04)	42	27.7 (0.05)	33	0.074
Log U-Voluine¹	154	2.0 (0.02)	34	2.49 (0.03)	45	0.108
		2.0 (0.02)	42	2.49 (0.03)	33	0.074
U-Na⁸	154	8.0 (0.3)	36	17.1 (0, 9)	43	0.259
		8.2 (0.4)	41	17.3 (1.2)	34	0.167
Log FE-UA^f	154	0.78 (0.01)	36	0.99 (0.01)	43	0, 259
		0.70 (0.03)	41	1.0 (0.02)	34	0.167
Log U-N-Alb-Pⁱ	148	1.08 (0.03)	41	1.57(0.03)	35	0.324
		1.14(0.03)	33	1.66 (0.05)	39	0.074
Log U_NP/P_NF ^k	148	-0.30 (0.03)	41	0.21 (0.03)	35	0.413
		-0.24 (0, 03)	34	0.33 (0.05)	38	0.257
Log (Um/Pm)¹	154	-1.23 (0.03)	39	-0, 69 (0.04)	40	0.865
		-1.19(0.03)	36	-0.67 (0.04)	39	0.497

U: urine, B: blood, P: plasma
^a-1: Median (range), followed by dimension:
^a: 6.12(4.41-7.60)
^b: 23.5 (18.0-30.6), mM I^-1
^c: 80 (60 - 110), mm Hg
^d: 348 (159-593), μM - I^-1
^e; 23, 9 (12-43), mg 1^-1
^f: 2, 21 (1.78 -2.86), ml
^g;154(2.3-47.1), mM
^h: 0.87 (-1.18-1.38),%
ⁱ: 1.34 (0.7-2.6), mg - I^-1
^k: -0.036 (-1.05 1.24)
^l:-0.94 (-1.8 - 0.15)
* **: below and above medians, respectively;
***: data are mean values (SE); note that intra-strala differences were insignificant (p > 0.05), except in parameters ^e (Low: SF vs. SB, p = 0.001) and ^h (Low: SFvs. SB, p = 0.015);
⁺: Total number of patients;
⁺⁺: p-valuc (Chi-squarc, 1 degree of freedom);
⁺⁺⁺: p-value (Fisher exact, 1-tailed test).

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