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Table 7 Appendix III. Simple correlation of 33 paired observations and components of MRA; *: For abbreviations and dimensions see Tables I, 2a, 2b, APP I, II; **: IRCU area considered; +: coefficient and pertinent p-value in SF and SB, respectively; ++: partial coefficient and pertinent p-value of positions included in MRA (see Table 4);x: correlation based on logio data

From: Idiopathic recurrent calcium urolithiasis (IRCU): pathophysiology evaluated in light of oxidative metabolism, without and with variation of several biomarkers in fasting urine and plasma - a comparison of stone-free and -bearing male patients, emphasizing mineral, acid-base, blood pressure and protein status

  

Variables*

 

SF

    

SB

     

Posi-

tions

Blocks**

Influential

Dependent

n

r +

p +

beta ++

p ++

N

r +

p +

beta ++

p ++

Remarks

1

 

FE-Na

U-pH

79

0.22

0.05

-0.12

0.38

75

0.12

0.31

-0.004

0.98

 

2

 

FE-K

U-pH

77

0.32

0.005

0.32

0.01

55

0.19

0.11

0.19

0.27

 

3

 

B-pH

U-pH

79

0.28

0.01

  

75

0.01

0.93

   

4

"Acid-

B-HCO3 -

-

U-pH

79

0.38

0.001

0.36

< 0.001

75

0.09

0.94

-0.06

0.64

 

5

Base"

B-HC03 -

UM

79

0.28

0.01

0.09

0.45

75

0.07

0.55

-0.23

0.07

 

6

 

U-Nax

U-Volume"

79

0.49

< 0.001

0.35

< 0.001

75

0.58

< 0.001

0.04

0.8

 

7

 

FE-Na

U-Volumcx

79

0.31

0.006

  

79

0.31

0.001

   

8

 

(U-HX + U-XA)x

U-pH

33

0.44

0.01

  

30

0.36

0.05

  

a

1

 

SS-CaOx

D-BP

61

-0.31

0.01

  

62

-0.15

0.24

   

2

 

U-MDAx

D-BP

65

0.29

0.02

0.27

0.12

65

0.16

0.21

-0.12

0.31

 

3

"Blood

P-PTH

D-BP

64

0.27

0.03

  

63

0.17

0.20

   

4

Pressure,

U-NITx

FE-UA*

52

-0.29

0.03

0.02

0.90

65

0.04

0.77

0.08

0.5

 

5

Uric acid"

P-UA

D-BP

65

0.26

0.04

  

65

0.04

0.60

   

6

 

BMI

D-BP

65

0.25

0.05

0.13

0.41

65

0.47

< 0.001

0.48

< 0.001

 

7

 

BMI

P-UA

79

0.29

0.01

-0.29

0.05

75

0.26

0.02

-0.40

< 0.001

 

1

 

U-NITX

P np

52

-0.31

0.02

-0.33

0.34

65

0.02

0.88

-0.53

0.07

 

2

 

U-MDAX ,

Pnp

79

-0.13

0.25

-0.79

0.07

75

0.31

0.007

1.15

0.004

 

3

 

(U-NIT/P-UA)x

Pnp

52

-0.38

0.005

-0.01

0.97

65

-0.03

0.8

0.45

0.13

b

4

"Protein"

(U-MDA/P-UA)X

Pnp

79

-0.26

0.02

-0.91

0.04

75

0.22

0.06

-1.02

0.02

c

5

 

P-UA

Pnp

76

0.38

0.001

-0.23

0.04

72

0.12

0.32

-0.15

0.19

 

6

 

(UNP/PNP)

U-Volume

75

-0.26

0.02

0.27

0.10

73

-0.3

0.01

-0.34

0.004

 

1

 

(UM/PM)x

UM/(U-Cit)x

78

0.71

0.001

0.49

0.001

75

0.71

< 0.001

0.63

< 0.001

d

2

 

(UM/PM)x

UM/(U-Mg)x

79

0.71

0.001

0.41

0.001

75

0.63

< 0.001

0.19

0.26

d

3

 

(UM/PM)x

U-pH

79

0.25

0.02

-0.07

0.40

75

-0.27

0.02

-0.20

0.01

 

4

'Calcium"

(UM/PM)x

(U-Na + U-K)*

79

0.41

0.001

-0.03

0.77

75

0.06

0.60

-0.22

0.01

 

5

 

(UM/PM)x

(UNP/PNP)x

76

-0.002

0.99

-0.23

0.007

72

-0.02

0.87

0.15

0.08

 

6

 

P-PTH

PM

77

0.32

0.004

0.43

0.002

72

0.05

0.69

-0.02

0.91

 

7

 

U-NITX

PM

52

-0.09

0.51

-0.10

0.44

65

-0.34

0.005

-0.33

0.01

 

8

 

BMI

PM

79

0.26

0.02

0.18

0.18

75

-0.08

0.52

-0.09

0.49

 

9

 

BMI

U-HXX

33

0.41

0.02

  

30

-0.29

0.12

  

a

10

 

U-NITX

P-PTH

50

-0.05

0.71

  

63

-0.33

0.009

  

e

11

 

(U-NIT/P-UA)X

P-PTH

50

-0.08

0.6

  

63

-0.39

0.002

  

e

12

 

P-PTH

1.25(OH)2D

73

0.27

0.02

  

68

0.25

0.04

  

e

  1. a: position not included in MRA (low number of observations detracts from power of statistical testing); b. c: in SF patients a role of P-UA as antioxidant appears indeterminate;
  2. d: positions appear modified by U-volume (see position 6 in block Protein) but were included in MRA; e: positions not included in MRA