Figure 4

Quantification of immunohistochemistry analysis. Immunohistochemistry analysis of lesion composition (n = 30) of INO-1001 treated mice compared to controls were performed. Number of positive cells were related to lesion area (CD3 (A)), related per plaque (CD3 (B), VCAM-1 (D)), to total number of cells in the adventitia (CD11c (C)) and to DAPI+ cells in the lesion (TUNEL (E)) in INO-1001 treated and control mice. Results are shown as box plots displaying medians and 25th and 75th percentiles as boxes and 10th and 90th percentiles as whiskers, n.s. = not significant.