Increased levels of anti-glycan antibodies in adults patients with CF. comparison of anti-glycan antibodies (% of sera positive results with CI95%) between children and adult patients with cystic fibrosis (CF). Positive anti glycan titer were defined as ≥ 50 U/ml. X-axis indicates patients positive for gASCA only (gASCA pos), or gASCA and additional antiglycan antibodies at the time (+ ≥ 1Ab; ≥ 2Ab, ≥ 3Ab). Asterisks indicate statistical significance for difference between CF children and adults (p < 0.002, Fisher's exact test after Bonferroni's adjustment).