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Table 2 Performance characteristics of anti-glycan antibodies for detection of patients with Crohn's disease

From: Increased levels of anti-glycan antibodies in patients with cystic fibrosis

  SE SP PPV NPV ACC
gASCA only 76.5 91.8 86.7 84.9 85.5
gASCA+1Ab 41.2 95.9 87.5 70.1 73.5
gASCA+2Ab 17.6 100 100.0 63.6 66.3
gASCA+3Ab 2.9 100 100.0 59.8 60.2
  1. SE = sensitivity; SP = specificity; PPV = positive predictive value; NPV = negative predictive value; ACC = accuracy; Ab anti-glycan antibodies (ACCA, ALCA, AMCA). Sera positive antibody titers were defined as ≥ 50 U/ml.