Skip to main content

Table 2 Studies on photodynamic therapy in unresectable cholangiocarcinoma

From: Feasibility and safety of long-term photodynamic therapy (PDT) in the palliative treatment of patients with hilar cholangiocarcinoma

Study

Year

Study type

Number of patients

Mean PDT sessions (range)

Median survival (months)

Adverse events: phototoxicity, cholangitis

Ortner

1998

Single arm

9

1.5 (1-2)

14.6

1 (11%), 0 (0%)

Berr

2000

Single arm

23

3 (1-5)

11.1

3 (13%), 8 (35%)

Zoepf

2001

Single arm

8

1-2

4

0, 2 (25%)

Rumalla

2001

Single arm

6

2.3 (1-2)

>6

2 (33%), 2 (33%)

Dumoulin

2003

Single arm

24

1-2

9.9

2 (8%), 5 (21%)

Ortner

2003

Randomized

39

2.4 (1-5)

16.4

2 (10%), 5 (25%)

Ortner

2003

Nonrandomized

31

1.5 (1-4)

14.2

3 (10%), 6 (19%)

Harewood

2005

Single arm

8

2 (1-5)

9.2

2 (25%), 2 (25%)

Shim

2005

Single arm

24

1-4

18.6

1 (4%) liver abscess

Zoepf

2005

Randomized

32

1-3

20.6

0, 4 (25%)

Witzigmann

2006

Single arm

68

2 (1-6)

12

8 (12%), 38 (56%)

Prasad

2007

Single arm

25

1.6 (1-4)

13.4

1 (4%), 2 (8%)

Fuks

2009

Single arm

14

2 (1-4)

13.8

2 (14%), 8 (57%)

This study

2010

Single arm

10

8 (4-14)

>25

1 (10%), 2 (20%)