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Table 1 Insulin secretion of non-cryopreserved non-encapsulated, non-cryopreserved encapsulated and cryopreserved encapsulated rat islets in a static incubation assay before, 12 and 56 weeks after transplantation

From: Long-term graft function of cryostored alginate encapsulated rat islets

 

Non-encapsulated

Non-cryopreserved encapsulated

Cryopreserved encapsulated

Time

Basal

(ng/islet/1,5h)

Stimulated

(ng/islet/1,5h)

Basal

(ng/islet/1,5h)

Stimulated

(ng/islet/1,5h)

Basal

(ng/islet/1,5h)

Stimulated

(ng/islet/1,5h)

before

2.9 ± 1.0

22.1 ± 5.5

2.1 ± 0.3

15.8 ± 4.6

2.0 ± 0.6

16.5 ± 4.0

*12 weeks

-

-

1.8 ± 0.5

15.1 ± 2.7

2.0 ± 0.7

14.9 ± 2.1

*56 weeks

-

-

1.9 ± 0.6

15.7 ± 4.3

2.2 ± 0.4

15.1 ± 4.3

  1. Data are given as mean ± SE; n = 3 independent experiments; *Measurements were performed after retrieval