Table 1 Clinico-pathological characteristics and treatment of adult patients suffering from PDLG with malignant astrocytic cells including our case

43

M

< 1

headache, nausea, facial nerve paresis

Cr, SC

-

+

-

-

[15]

51

M

2

IRP, back pain

Cr, SC

+

-

-

+ CYC, ADR, 5FU, MTX it

[10]

47

M

2

headaches, altered consciousness, numbness in both arms

Cr

+

-

-

+ MTX it

[16]

23

F

< 3

IRP, seizures

Cr

-

+

-

-

[12]

52

M

3

low back pain, numbness of both legs

Cr, SC

+

+

+ (craniospinal)

+ MCNU, Interferon

[17]

63

F

3

IRP, headache, coma

Cr, BrS

+

+

-

+ CYC

[11]

19

M

3

IRP

Cr, SC

-

+

-

-

[18]

25

M

5

IRP

Cr, BrS, SC

+

+

-

-

[19]

71

M

7

back stiffness

SC

-

+

-

-

[2]

50

M

7

IRP, polyneuritis cranialis

Cr, BrS, SC

+

+

-

-

[5]

19

M

11

holocephalic headache, nausea, vomitus, left-sided weakness

Cr, SC

+

-

+ (craniospinal)

+ TMZ

[13]

60

M

12

blurred vision, back pain

SC

+

-

+ (spinal)

-

[20]

24

M

13

holocephalic headache, neck pain, diplopia, confusion

Cr, SC

+

-

-

+ 12c × TMZ/BCNU

[13]

40

F

17

ataxia, incontinence, obstipation

Cr

+

-

-

+ 7c × TMZ, AUC + ETO, BCNU

[14]

53

M

24

seizures, gait disturbance, paraparesis, sensory disturbance

Cr, SC

+

-

+ (craniospinal)

+11c xTMZ, INN, DDP, INT, BVZ

our case