From: Reversal of cerebral radiation necrosis with bevacizumab treatment in 17 Chinese patients
Pt. No | Age (y) | Sex | Underlying disease | Radiation treatment | Radiation necrosis site | Last RT to study entry (mo) | % Change in Gadolinium | % Change in T2W | Radiologic follow-up | KPS*# | Steroids**# (mg) |
---|---|---|---|---|---|---|---|---|---|---|---|
1 | 70 | M | Colon cancer | SRS 17 Gy | Left temporal | 6 | 0 | 0 | 4 | 30 → 30 | 15 → 12.5 |
2 | 13 | F | Anaplastic Astrocytoma | EBRT 56 Gy | Right thalamus | 18 | 75 | 60 | 9 | 50 → 70 | 10 → 0 |
3 | 71 | M | Colon cancer | EBRT 36 Gy | Left frontal | 4 | 65 | 10 | 6 | 40 → 80 | 15 → 5 |
4 | 52 | F | meningioma | EBRT 60 Gy | Right frontal | 180 | 80 | 60 | 8 | 60 → 90 | 10 → 2.5 |
5 | 71 | M | Lung cancer | FSRT 31.5 Gy/3 fx | Left occipital | 7 | 87 | 78 | 8 | 50 → 90 | 15 → 0 |
6 | 48 | M | Glioblastoma | EBRT 60 Gy | Left frontal | 7 | 80 | 75 | 5 | 50 → 70 | 10 → 2.5 |
7 | 32 | F | Anaplastic oligodendroglioma | EBRT 60 Gy | Right frontal | 40 | 50 | 45 | 4 | 50 → 70 | 15 → 10 |
8 | 67 | F | Colon cancer | 1.EBRT 39 Gy /13 fx | Right frontal | 1 | 52 | 78 | 4 | 50 → 90 | 15 → 0 |
2.SRS 16 Gy | |||||||||||
9 | 23 | M | AVM | SRS 16 Gy | Left basal ganglia | 21 | 50 | 40 | 3 | 70 → 80 | 10 → 5 |
10 | 26 | M | Fibrous dysplasia of bone | EBRT 70 Gy | Brain stem | 132 | 65 | 55 | 4 | 50 → 70 | 17.5 → 5 |
11 | 62 | M | Glioblastoma | EBRT 60 Gy | Left frontal | 9 | 73 | 61 | 8 | 30 → 50 | 15 → 5 |
12 | 65 | M | Glioblastoma | EBRT 60 Gy | Right frontal | 4 | 30 | 45 | 6 | 60 → 70 | 10 → 2.5 |
13 | 41 | M | Glioblastoma | FSRT 30 Gy/6 fx | Left basal ganglia | 15 | 60 | 50 | 8 | 50 → 90 | 15 → 2.5 |
14 | 45 | M | Glioblastoma | FSRT 25.2 Gy/6 fx | Right thalamus | 4 | 33 | 76 | 6 | 60 → 90 | 15 → 2.5 |
15 | 46 | M | Lung cancer | 1.EBRT 30 Gy/10 fx | Left occipital | 5 | 50 | 30 | 8 | 60 → 80 | 12.5 → 5 |
2.SRS 16 Gy | |||||||||||
16 | 34 | M | Glioblastoma | EBRT 60 Gy | Right temporal | 5 | 75 | 54 | 4 | 60 → 80 | 15 → 5 |
17 | 55 | M | Glioblastoma | EBRT 56 Gy | Right temporal | 6 | 60 | 65 | 8 | 40 → 60 | 10 → 0 |