Skip to main content

Table 3 Genotypic and allelic frequencies of SNPs from ZBTB17, HSPB7 , and ACTC1 genes in DCM patients and controls

From: Polymorphism of ZBTB17 gene is associated with idiopathic dilated cardiomyopathy: a case control study in a Han Chinese population

Marker

Genotype

Allele

P value

OR(95% CI)

ZBTB17

    

rs10927875

C/C

C/T

TT

C

T

0.05

5.19(1.00, 27.03)

Patients

88(0.946)

5(0.054)

0

181(0.973)

5(0.054)

  

Controls

187(0.989)

2(0.011)

0

376(0.995)

2(0.011)

  

HSPB7

       

rs1739843

C/C

C/T

T/T

C

T

0.81

0.95(0.64, 1.42)

Patients

49(0.521)

43(0.457)

2(0.021)

141(0.75)

47(0.250)

  

Controls

103(0.545)

74(0.392)

12(0.063)

280(0.741)

98(0.259)

  

rs7523558

A/A

A/G

G/G

A

G

0.96

0.98(0.52, 1.87 )

Patients

0(0)

15(0.161)

78(0.839)

15(0.081)

171(0.919)

  

Controls

1(0.005)

29(0.153)

159(0.841)

31(0.082)

347(0.918)

  

rs6660685

A/A

A/G

G/G

A

G

0.11

3.29(0.78, 13.91)

Patients

0

5(0.053)

90(0.947)

5(0.026)

185(0.974)

  

Controls

0

3(0.016)

181(0.984)

3(0.008)

365(0.992)

  

ACTC1

       

rs533021

C/C

C/T

T/T

C

T

0.36

1.19(0.82, 1.73)

Patients

13(0.149)

39(0.448)

35(0.402)

65(0.374)

109(0.626)

  

Controls

21(0.111)

84(0.444)

84(0.444)

126(0.333)

252(0.667)

  

rs589759

C/C

C/T

T/T

C

T

0.25

1.22(0.87, 1.73)

Patients

25(0.258)

48(0.495)

24(0.247)

98(0.505)

96(0.495)

  

Controls

54(0.286)

102(0.540)

33(0.175)

210(0.556)

168(0.444)

  

rs1370154

A/A

A/G

G/G

A

G

0.77

0.93(0.58, 1.50)

Patients

7(0.156)

18(0.4)

20(0.444)

32(0.356)

58(0.644)

  

Controls

26(0.141)

85(0.462)

73(0.397)

137(0.372)

231(0.628)

  

rs2070664

A/A

A/G

G/G

A

G

0.84

1.04(0.73, 1.47)

Patients

33(0.344)

42(0.438)

21(0.219)

108(0.562)

84(0.438)

  

Controls

62(0.328)

92(0.487)

35(0.185)

216(0.571)

162(0.429)

  

rs3759834

C/C

C/T

T/T

C

T

0.72

0.82(0.29, 2.37)

Patients

0

5(0.053)

90(0.947)

5(0.026)

185(0.974)

  

Controls

0

12(0.063)

177(0.937)

12(0.032)

366(0.968)

  

rs525720

A/A

A/G

G/G

A

G

0.42

0.81(0.48, 1.36)

Patients

2(0.022)

19(0.211)

69(0.767)

23(0.128)

157(0.872)

  

Controls

3(0.016)

52(0.275)

134(0.709)

58(0.153)

320(0.847)

  

rs670957

A/A

A/G

G/G

A

G

0.09

1.36(0.95, 1.94)

Patients

19(0.211)

44(0.489)

27(0.3)

82(0.456)

98(0.544)

  

Controls

55(0.293)

90(0.479)

43(0.229)

200(0.532)

176(0.468)

  
  1. CI, confidence interval; OR, odds ratio in which the minor allele was viewed as an exposure factor in the case-controlled study.