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Table 1 The expression of virulence gene CpsA of Streptococcus pneumoniae (SP) before and after stimulation of THP-1 and A549 cells

From: Roles of virulence genes (PsaA and CpsA) on the invasion of Streptococcus pneumoniae into blood system

Group

Number

THP-1(ΔCta, mean ± SD.)

A549(ΔCt, mean ± SD.)

0 hours

4 hours

8 hours

0 hours

4 hours

8 hours

ATCC49619

1

9.8

11.7

25.3

9.8

17.6

11.7

Blood-derived SP

11

24.0 ± 2.1b

14.6 ± 6.2

17.1 ± 4.2b

24.0 ± 2.1b

16.5 ± 4.7

15.1 ± 3.0b

Sputum-derived SP

12

23.9 ± 2.2b

16.9 ± 4.9

18.8 ± 2.6b

23.9 ± 2.2b

15.1 ± 4.6

16.8 ± 5.0b

  1. aΔ Ct = Mean Ct of tested gene - Mean Ct of control gene.
  2. bP < 0.05, compared with ATCC49619 at same time point.