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Table 1 The expression of virulence gene CpsA of Streptococcus pneumoniae (SP) before and after stimulation of THP-1 and A549 cells

From: Roles of virulence genes (PsaA and CpsA) on the invasion of Streptococcus pneumoniae into blood system

Group Number THP-1(ΔCta, mean ± SD.) A549(ΔCt, mean ± SD.)
0 hours 4 hours 8 hours 0 hours 4 hours 8 hours
ATCC49619 1 9.8 11.7 25.3 9.8 17.6 11.7
Blood-derived SP 11 24.0 ± 2.1b 14.6 ± 6.2 17.1 ± 4.2b 24.0 ± 2.1b 16.5 ± 4.7 15.1 ± 3.0b
Sputum-derived SP 12 23.9 ± 2.2b 16.9 ± 4.9 18.8 ± 2.6b 23.9 ± 2.2b 15.1 ± 4.6 16.8 ± 5.0b
  1. aΔ Ct = Mean Ct of tested gene - Mean Ct of control gene.
  2. bP < 0.05, compared with ATCC49619 at same time point.