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Table 1 Distribution of body weight, total serum cholesterol, LDL cholesterol, HDL cholesterol, and serum triglycerides of recipients of GDF-15 −/− bone marrow (GDF-15 −/− ) and wild-type controls (GDF-15 +/+ ) ( p was non-significant)

From: GDF-15 protects from macrophage accumulation in a mousemodel of advanced atherosclerosis

 

Body weight (g)

Total cholesterol (mg/dL)

LDL cholesterol (mg/dL)

HDL cholesterol (mg/dL)

Triglycerides (mg/dL)

Lesion size (μm2)

GDF-15 +/+ (WT)(n=15)

28±1

351±28

293±26

25±2

159±20

246,566±14,788†

GDF-15 −/− (KO)(n=17)

29±1

364±15

309±14

28±3

134±5

203,079±17,898†

  1. Quantitative evaluation of lesion size within the aortic root also showed no significant difference between the groups (p=0.08); Mean±SEM; †p=0.08.
  2. WT: wild-type (recipients of bone marrow from C57/Black 6 control mice); KO: knock-out (recipients of bone marrow from GDF-15 negative mice).