Figure 2
A case with chronic tubular interstitial nephritis (TIN) and diabetic nephropathy (DN). (A) Deposits of mainly IgG collected in the basement membrane and appeared in a linear pattern as viewed by immunofluorescence (IF, 200×). (B) (PAS, 100×) and (C) (Masson, 100×) show severe mesangial expansion (Kimmelstiel-Wilson nodules) and severe tubular injury with only minimal cell infiltration in the interstitial area. DN, diabetic nephropathy; IF, immunofluorescence; IgG, immunoglobulin G; PAS, periodic acid-Schiff; TIN, tubular interstitial nephritis.