Effect of THR and TKR surgery on platelet counts. The points represent mean ± SD. P = 0.013 (n = 5), as determined by ANOVA (THR). Upon further testing, the pairwise comparison showed significant differences between baseline vs day 3 postoperative (*P = 0.04). ANOVA, analysis of variance; SD, standard deviation; THR, total hip replacement; TKR, total knee replacement.