Figure 4

Hepatic mRNA expression of tumor necrosis factor (TNF)-α, interferon (IFN)-γ and hemeoxygenase (HO)-1 assessed by reverse transcription-quantitative PCR after 8 weeks of dietary intake with diethylnitrosamine in drinking water. (A) Hepatic expression TNF-α mRNA in rats fed a high-fructose diet was similar to that in rats fed a high-fat or control diet. (B) Hepatic expression of IFN-γ mRNA tended to be higher in rats fed a high-fructose diet compared to that in rats fed a high-fat or control diet. (C) Hepatic expression of HO-1 mRNA tended to be lower in rats fed a high-fructose diet compared to that in rats fed a high-fat or control diet. *mRNA level normalized using that of β-actin. Values are means ± standard deviation of 8 rats.