Dietary fructose enhances the incidence of precancerous hepatocytes induced by administration of diethylnitrosamine in rat

Table 1 Serum biochemical markers after 8 weeks of diet intake

	Control	High fat	High fructose	P value*
ALT (IU/L)	13.5 ± 5.2	26.1 ± 9.9	23.9 ± 10.0	0.01
Total cholesterol (mg/dL)	60.8 ± 7.7	57.6 ± 6.4	69.0 ± 15.7	0.37
Triglyceride (mg/dL)	104.3 ± 37.3	49.1 ± 13.2^#	149.7 ± 54.6^##	0.001
Fasting blood glucose (mg/dL)	133.4 ± 15.9	109.8 ± 31.3^#	151.6 ± 14.2^##	0.01
Insulin (ng/mL)	3.58 ± 1.89	3.23 ± 1.27	5.92 ± 1.80^##	0.03

Data are shown as mean ± standard deviation. ALT, Alanine aminotransferase. *P values determined by Kruskal-Wallis test. ^#P <0.05 vs. control group (Games-Howell test). ^##P <0.05 vs. high-fat group (Games-Howell test).

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