Dietary fructose enhances the incidence of precancerous hepatocytes induced by administration of diethylnitrosamine in rat

Table 2 Precancerous hepatocytes induced by oral administration of DEN with 8 weeks of diet

	Control	High fat	High fructose	P value*
The number of slides containing GST-P-positive hepatocytes in 24 slides	6	9	15	0.03
The number of GST-P-positive hepatocytes in 360 fields	7	12	212	<0.001
The number of GST-P-positive hepatocytes in GST-P positive slides	1.17 ± 0.41	1.33 ± 0.71	14.1 ± 37.9	0.03

Data are shown as the number or mean ± standard deviation. *P values determined by χ² test or Kruskal-Wallis test, as appropriate.

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