Figure 4

Comparison expression of heat shock protein (HSP)70, MICA and MICB protein with or without MS-275. (A) Western blot showing the protein band of HSP70, MICA and MICB at the molecular weights of 147, 73 and 47 kDa, respectively. EMD, exosomes with drug modification; EWD, exosomes without drug modification. (B) Histogram comparison; after treatment with MS-275, the expression of MICA, MICB and HSP70 in HepG2 cell exosomes (EMD) increased significantly compared with untreated cells (EWD).