TY - JOUR AU - Catania, R. A. AU - Angele, M. K. AU - Ayala, A. AU - Cioffi, W. G. AU - Bland, K. I. AU - Chaudry, I. H. PY - 1999 DA - 1999// TI - Dehydroepiandrosterone restores immune function following trauma-haemorrhage by a direct effect on T lymphocytes JO - Cytokine VL - 11 UR - https://doi.org/10.1006/cyto.1998.0458 DO - 10.1006/cyto.1998.0458 ID - Catania1999 ER - TY - JOUR AU - Angele, M. K. AU - Catania, R. A. AU - Ayala, A. AU - Cioffi, W. G. AU - Bland, K. I. AU - Chaudry, I. H. PY - 1998 DA - 1998// TI - Dehydroepiandrosterone: an inexpensive steroid hormone that decreases the mortality due to sepsis following trauma-induced hemorrhage JO - Arch Surg VL - 133 UR - https://doi.org/10.1001/archsurg.133.12.1281 DO - 10.1001/archsurg.133.12.1281 ID - Angele1998 ER - TY - JOUR AU - Ben-Nathan, D. AU - Padgett, D. A. AU - Loria, R. M. PY - 1999 DA - 1999// TI - Androstenediol and dehydroepiandrosterone protect mice against lethal bacterial infections and lipopolysaccharide toxicity JO - J Med Microbiol VL - 48 UR - https://doi.org/10.1099/00222615-48-5-425 DO - 10.1099/00222615-48-5-425 ID - Ben-Nathan1999 ER - TY - JOUR AU - Straub, R. H. AU - Konecna, L. AU - Hrach, S. AU - Rothe, G. AU - Kreutz, M. AU - Scholmerich, J. AU - Falk, W. AU - Lang, B. PY - 1998 DA - 1998// TI - Serum dehydroepiandrosterone (DHEA) and DHEA sulfate are negatively correlated with serum interleukin-6 (IL-6), and DHEA inhibits IL-6 secretion from mononuclear cells in man in vitro: possible link between endocrinosenescence and immunosenescence JO - J Clin Endocrinol Metab VL - 83 UR - https://doi.org/10.1210/jcem.83.6.4876 DO - 10.1210/jcem.83.6.4876 ID - Straub1998 ER - TY - JOUR AU - Weiss, E. P. AU - Villareal, D. T. AU - Fontana, L. AU - Han, D. H. AU - Holloszy, J. O. PY - 2011 DA - 2011// TI - Dehydroepiandrosterone (DHEA) replacement decreases insulin resistance and lowers inflammatory cytokines in aging humans JO - Aging (Albany NY) VL - 3 ID - Weiss2011 ER - TY - JOUR AU - Shimizu, T. AU - Szalay, L. AU - Choudhry, M. A. AU - Schwacha, M. G. AU - Rue, L. W. AU - Bland, K. I. AU - Chaudry, I. H. PY - 2005 DA - 2005// TI - Mechanism of salutary effects of androstenediol on hepatic function after trauma-hemorrhage: role of endothelial and inducible nitric oxide synthase JO - Am J Physiol Gastrointest Liver Physiol VL - 288 UR - https://doi.org/10.1152/ajpgi.00387.2004 DO - 10.1152/ajpgi.00387.2004 ID - Shimizu2005 ER - TY - JOUR AU - Kobbe, P. AU - Kaczorowski, D. J. AU - Vodovotz, Y. AU - Tzioupis, C. H. AU - Mollen, K. P. AU - Billiar, T. R. AU - Pape, H. C. PY - 2008 DA - 2008// TI - Local exposure of bone components to injured soft tissue induces toll-like receptor 4-dependent systemic inflammation with acute lung injury JO - Shock VL - 30 UR - https://doi.org/10.1097/SHK.0b013e31816f257e DO - 10.1097/SHK.0b013e31816f257e ID - Kobbe2008 ER - TY - JOUR AU - Kobbe, P. AU - Vodovotz, Y. AU - Kaczorowski, D. J. AU - Mollen, K. P. AU - Billiar, T. R. AU - Pape, H. C. PY - 2008 DA - 2008// TI - Patterns of cytokine release and evolution of remote organ dysfunction after bilateral femur fracture JO - Shock VL - 30 UR - https://doi.org/10.1097/SHK.0b013e31815d190b DO - 10.1097/SHK.0b013e31815d190b ID - Kobbe2008 ER - TY - JOUR AU - Menzel, C. L. AU - Pfeifer, R. AU - Darwiche, S. S. AU - Kobbe, P. AU - Gill, R. AU - Shapiro, R. A. AU - Loughran, P. AU - Vodovotz, Y. AU - Scott, M. J. AU - Zenati, M. S. AU - Billiar, T. R. AU - Pape, H. C. PY - 2011 DA - 2011// TI - Models of lower extremity damage in mice: time course of organ damage and immune response JO - J Surg Res VL - 166 UR - https://doi.org/10.1016/j.jss.2010.11.914 DO - 10.1016/j.jss.2010.11.914 ID - Menzel2011 ER - TY - JOUR AU - Kobbe, P. AU - Micansky, F. AU - Lichte, P. AU - Sellei, R. M. AU - Pfeifer, R. AU - Dombroski, D. AU - Lefering, R. AU - Pape, H. C. AU - TraumaRegister, D. G. U. PY - 2013 DA - 2013// TI - Increased morbidity and mortality after bilateral femoral shaft fractures: myth or reality in the era of damage control? JO - Injury VL - 44 UR - https://doi.org/10.1016/j.injury.2012.09.011 DO - 10.1016/j.injury.2012.09.011 ID - Kobbe2013 ER - TY - JOUR AU - Bonnarens, F. AU - Einhorn, T. A. PY - 1984 DA - 1984// TI - Production of a standard closed fracture in laboratory animal bone JO - J Orthop Res VL - 2 UR - https://doi.org/10.1002/jor.1100020115 DO - 10.1002/jor.1100020115 ID - Bonnarens1984 ER - TY - JOUR AU - Kobbe, P. AU - Vodovotz, Y. AU - Kaczorowski, D. J. AU - Billiar, T. R. AU - Pape, H. C. PY - 2008 DA - 2008// TI - The role of fracture-associated soft tissue injury in the induction of systemic inflammation and remote organ dysfunction after bilateral femur fracture JO - J Orthop Trauma VL - 22 UR - https://doi.org/10.1097/BOT.0b013e318175dd88 DO - 10.1097/BOT.0b013e318175dd88 ID - Kobbe2008 ER - TY - JOUR AU - Strecker, W. AU - Gebhard, F. AU - Rager, J. AU - Bruckner, U. B. AU - Steinbach, G. AU - Kinzl, L. PY - 1999 DA - 1999// TI - Early biochemical characterization of soft-tissue trauma and fracture trauma JO - J Trauma VL - 47 UR - https://doi.org/10.1097/00005373-199908000-00025 DO - 10.1097/00005373-199908000-00025 ID - Strecker1999 ER - TY - JOUR AU - Schmitz, D. AU - Kobbe, P. AU - Wegner, A. AU - Hammes, F. AU - Oberbeck, R. PY - 2010 DA - 2010// TI - Dehydroepiandrosterone during sepsis: does the timing of administration influence the effectiveness JO - J Surg Res VL - 163 UR - https://doi.org/10.1016/j.jss.2010.05.017 DO - 10.1016/j.jss.2010.05.017 ID - Schmitz2010 ER - TY - JOUR AU - Oberbeck, R. AU - Dahlweid, M. AU - Koch, R. AU - van Griensven, M. AU - Emmendorfer, A. AU - Tscherne, H. AU - Pape, H. C. PY - 2001 DA - 2001// TI - Dehydroepiandrosterone decreases mortality rate and improves cellular immune function during polymicrobial sepsis JO - Crit Care Med VL - 29 UR - https://doi.org/10.1097/00003246-200102000-00029 DO - 10.1097/00003246-200102000-00029 ID - Oberbeck2001 ER - TY - JOUR AU - Hildebrand, F. AU - Pape, H. C. AU - Krettek, C. PY - 2005 DA - 2005// TI - The importance of cytokines in the posttraumatic inflammatory reaction JO - Unfallchirurg VL - 108 UR - https://doi.org/10.1007/s00113-005-1005-1 DO - 10.1007/s00113-005-1005-1 ID - Hildebrand2005 ER - TY - JOUR AU - DeLong, W. G. AU - Born, C. T. PY - 2004 DA - 2004// TI - Cytokines in patients with polytrauma JO - Clin Orthop Relat Res VL - 422 UR - https://doi.org/10.1097/01.blo.0000130840.64528.1e DO - 10.1097/01.blo.0000130840.64528.1e ID - DeLong2004 ER - TY - JOUR AU - Aldridge, A. J. PY - 2002 DA - 2002// TI - Role of the neutrophil in septic shock and the adult respiratory distress syndrome JO - Eur J Surg VL - 168 UR - https://doi.org/10.1080/11024150260102807 DO - 10.1080/11024150260102807 ID - Aldridge2002 ER - TY - JOUR AU - Frevert, C. W. AU - Huang, S. AU - Danaee, H. AU - Paulauskis, J. D. AU - Kobzik, L. PY - 1995 DA - 1995// TI - Functional characterization of the rat chemokine KC and its importance in neutrophil recruitment in a rat model of pulmonary inflammation JO - J Immunol VL - 154 ID - Frevert1995 ER - TY - JOUR AU - Johnson, M. J. AU - Lucas, G. L. PY - 1996 DA - 1996// TI - Fat embolism syndrome JO - Orthopedics VL - 19 ID - Johnson1996 ER - TY - JOUR AU - Shaikh, N. PY - 2009 DA - 2009// TI - Emergency management of fat embolism syndrome JO - J Emerg Trauma Shock VL - 2 UR - https://doi.org/10.4103/0974-2700.44680 DO - 10.4103/0974-2700.44680 ID - Shaikh2009 ER - TY - JOUR AU - Barkhausen, T. AU - Hildebrand, F. AU - Krettek, C. AU - van Griensven, M. PY - 2009 DA - 2009// TI - DHEA-dependent and organ-specific regulation of TNF-alpha mRNA expression in a murine polymicrobial sepsis and trauma model JO - Crit Care VL - 13 UR - https://doi.org/10.1186/cc7963 DO - 10.1186/cc7963 ID - Barkhausen2009 ER - TY - JOUR AU - Oberbeck, R. AU - Deckert, H. AU - Bangen, J. AU - Kobbe, P. AU - Schmitz, D. PY - 2007 DA - 2007// TI - Dehydroepiandrosterone: a modulator of cellular immunity and heat shock protein 70 production during polymicrobial sepsis JO - Intensive Care Med VL - 33 UR - https://doi.org/10.1007/s00134-007-0851-4 DO - 10.1007/s00134-007-0851-4 ID - Oberbeck2007 ER - TY - JOUR AU - Svec, F. AU - Porter, J. R. PY - 1998 DA - 1998// TI - The actions of exogenous dehydroepiandrosterone in experimental animals and humans JO - Proc Soc Exp Biol Med VL - 218 UR - https://doi.org/10.3181/00379727-218-44285 DO - 10.3181/00379727-218-44285 ID - Svec1998 ER -