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Table 4 Characteristics of ventricular septal defect (VSD) among screened subjects ( n = 2,661)

From: Prenatal ultrasonography and Doppler sonography for the clinical investigation of isolated ventricular septal defects in a late second-trimester population

Variable

 

Normal (n = 2,537)

 

VSD (n = 124)

P value

Mean ± SD

10 to 90%

Mean ± SD

10 to 90%

NBL (mm)

6.74 ± 0.87

5.60 to 7.90

6.40 ± 0.79

5.30 to 7.40

<0.0001

BPD (mm)

54.33 ± 9.10

48.00 to 60.00

52.65 ± 4.87

47.12 to 59.70

0.041

HC (mm)

197.34 ± 15.57

177.00 to 218.00

193.94 ± 14.66

175.00 to 213.40

0.017

AC (mm)

177.08 ± 16.15

156.00 to 198.00

171.36 ± 16.12

150.82 to 194.45

<0.0001

Femur length (mm)

37.33 ± 3.86

32.50 to 42.40

35.93 ± 3.78

30.72 to 41.10

<0.0001

Tibia length (mm)

32.92 ± 3.42

28.30 to 37.30

31.90 ± 3.53

27.12 to 36.92

0.001

Fibula length (mm)

32.76 ± 3.33

28.35 to 37.00

31.71 ± 3.27

26.88 to 36.00

0.001

Humerus length (mm)

35.39 ± 3.34

31.00 to 39.70

34.40 ± 3.24

29.94 to 38.70

0.001

Radius length (mm)

30.34 ± 2.94

26.70 to 34.00

29.38 ± 2.70

25.70 to 32.46

<0.0001

Ulna length (mm)

32.92 ± 3.21

28.80 to 37.00

32.07 ± 3.14

28.00 to 36.30

0.004

Estimated FBW (g)

508.75 ± 116.48

364.00 to 666.00

470.74 ± 107.31

343.60 to 608.20

<0.0001

CTAR

0.22 ± 0.12

0.18 to 0.25

0.21 ± 0.03

0.18 to 0.25

0.753

CTCR

0.46 ± 0.06

0.42 to 0.50

0.46 ± 0.03

0.43 to 0.50

0.131

UA PI

1.16 ± 0.22

0.93 to 1.40

1.33 ± 0.34

0.99 to 1.91

<0.0001

UA RI

0.69 ± 0.08

0.60 to 0.78

0.74 ± 0.09

0.64 to 0.86

<0.0001

MCA PI

1.59 ± 0.27

1.26 to 1.90

1.48 ± 0.24

1.18 to 1.82

<0.0001

MCA RI

0.81 ± 0.08

0.72 to 0.91

0.79 ± 0.65

0.71 to 0.87

0.008

MCA/UA PI ratio

1.41 ± 0.34

1.02 to 1.79

1.19 ± 0.38

0.66 to 1.67

<0.0001

MCA/UA RI ratio

1.19 ± 0.18

0.99 to 1.40

1.09 ± 0.18

0.85 to 1.30

<0.0001

  1. AC, abdominal circumference; BPD, biparietal diameter; CTAR, cardiothoracic area ratio; CTCR, cardiothoracic circumference ratio; FBW, fetal body weight; HC, head circumference; MCA, middle cerebral artery; MCA/UA PI ratio, ratio of middle cerebral artery resistance index to umbilical artery pulsatility index; MCA/UA RI ratio, ratio of middle cerebral artery resistance index to umbilical artery resistance index; NBL, nasal bone length; PI, pulsatility index; RI, resistance index; SD, standard deviation; UA, umbilical artery; VSD, ventricular septal defect.