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Table 4 Characteristics of ventricular septal defect (VSD) among screened subjects ( n= 2,661)

From: Prenatal ultrasonography and Doppler sonography for the clinical investigation of isolated ventricular septal defects in a late second-trimester population

Variable   Normal (n = 2,537)   VSD (n = 124) P value
Mean ± SD 10 to 90% Mean ± SD 10 to 90%
NBL (mm) 6.74 ± 0.87 5.60 to 7.90 6.40 ± 0.79 5.30 to 7.40 <0.0001
BPD (mm) 54.33 ± 9.10 48.00 to 60.00 52.65 ± 4.87 47.12 to 59.70 0.041
HC (mm) 197.34 ± 15.57 177.00 to 218.00 193.94 ± 14.66 175.00 to 213.40 0.017
AC (mm) 177.08 ± 16.15 156.00 to 198.00 171.36 ± 16.12 150.82 to 194.45 <0.0001
Femur length (mm) 37.33 ± 3.86 32.50 to 42.40 35.93 ± 3.78 30.72 to 41.10 <0.0001
Tibia length (mm) 32.92 ± 3.42 28.30 to 37.30 31.90 ± 3.53 27.12 to 36.92 0.001
Fibula length (mm) 32.76 ± 3.33 28.35 to 37.00 31.71 ± 3.27 26.88 to 36.00 0.001
Humerus length (mm) 35.39 ± 3.34 31.00 to 39.70 34.40 ± 3.24 29.94 to 38.70 0.001
Radius length (mm) 30.34 ± 2.94 26.70 to 34.00 29.38 ± 2.70 25.70 to 32.46 <0.0001
Ulna length (mm) 32.92 ± 3.21 28.80 to 37.00 32.07 ± 3.14 28.00 to 36.30 0.004
Estimated FBW (g) 508.75 ± 116.48 364.00 to 666.00 470.74 ± 107.31 343.60 to 608.20 <0.0001
CTAR 0.22 ± 0.12 0.18 to 0.25 0.21 ± 0.03 0.18 to 0.25 0.753
CTCR 0.46 ± 0.06 0.42 to 0.50 0.46 ± 0.03 0.43 to 0.50 0.131
UA PI 1.16 ± 0.22 0.93 to 1.40 1.33 ± 0.34 0.99 to 1.91 <0.0001
UA RI 0.69 ± 0.08 0.60 to 0.78 0.74 ± 0.09 0.64 to 0.86 <0.0001
MCA PI 1.59 ± 0.27 1.26 to 1.90 1.48 ± 0.24 1.18 to 1.82 <0.0001
MCA RI 0.81 ± 0.08 0.72 to 0.91 0.79 ± 0.65 0.71 to 0.87 0.008
MCA/UA PI ratio 1.41 ± 0.34 1.02 to 1.79 1.19 ± 0.38 0.66 to 1.67 <0.0001
MCA/UA RI ratio 1.19 ± 0.18 0.99 to 1.40 1.09 ± 0.18 0.85 to 1.30 <0.0001
  1. AC, abdominal circumference; BPD, biparietal diameter; CTAR, cardiothoracic area ratio; CTCR, cardiothoracic circumference ratio; FBW, fetal body weight; HC, head circumference; MCA, middle cerebral artery; MCA/UA PI ratio, ratio of middle cerebral artery resistance index to umbilical artery pulsatility index; MCA/UA RI ratio, ratio of middle cerebral artery resistance index to umbilical artery resistance index; NBL, nasal bone length; PI, pulsatility index; RI, resistance index; SD, standard deviation; UA, umbilical artery; VSD, ventricular septal defect.