Table 3 Gene Ontology database enrichment analysis of cluster D
Gene Ontology term | Genes | P-value |
|---|---|---|
Response to DNA damage stimulus | PARP3, TOP2A, RAD51 | 0.0025 |
DNA metabolic process | PRIM1, RFC1, PARP3 | 0.0041 |
Chromosome organisation | CDCA8, H2AFX, RFC1 | 0.0047 |
Chromosome condensation | NCAPH, TOP2A | 0.0065 |
Chromosome segregation | MIS12, TOP2A | 0.0073 |
Cellular response to DNA damage stimulus | TOPBP1, PARP3, TOP2A | 0.0080 |
mRNA export from nucleus | AGFG1, RAE1 | 0.0089 |
DNA packaging | NCAPH, TOP2A | 0.0106 |
Response to ionizing radiation | TOPBP1, H2AFX | 0.0115 |
RNA export from nucleus | AGFG1, RAE1 | 0.0124 |
Endocytosis | SNX4, SFTPD, CD14 | 0.0150 |
Regulation of ubiquitin-protein ligase activity | BUB3, CDC23, CCNB1 | 0.0155 |
RNA transport | AGFG1, RAE1 | 0.0166 |
DNA repair | TOPBP1, PARP3, TOP2A | 0.0170 |
Nuclear export | AGFG1, RAE1 | 0.0290 |
DNA replication | RFC1, TOP2A, MCM5 | 0.0324 |
Organelle organisation | CDCA8, BUB3, H2AFX | 0.0357 |
Response to stress | PARP3, PHLDA3, LSP1 | 0.0359 |
Cellular response to stimulus | PARP3, TOP2A, RAD51 | 0.0375 |
Innate immune response | TUBB2C, SFTPD | 0.0441 |