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Table 3 BRCA1/2 mutation prevalence in unselected/selected triple-negative breast cancer (TNBC) patients

From: The prevalence of BRCA1/2 mutations of triple-negative breast cancer patients in Xinjiang multiple ethnic region of China

 

Number of cases

BRCA1 mutations (%)

BRCA2 mutations (%)

Total BRCA1/2 mutations (%)

All selected TN

35

7 (20)

3 (8.6)

9 (25.7)

< 35 years

6

1 (16.7)

1 (16.7)

2 (33.3)

≥ 35 years

29

6 (20.7)

2 (6.9)

7 (24.1)a

All unselected TN

61

11 (18)

4 (6.6)

15 (24.6)

< 35 years

20

4 (20)

1 (5)

5 (25)

≥ 35 years

41

7 (17.1)

3 (7.3)

10 (24.4)

  1. Selection criteria: Selected = bilateral breast cancer and/or family history of TNBC; Unselected = TNBC.
  2. aBoth BRCA1 and BRCA2 mutations were identified in one patient with family history, and she was 47 years old.