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Table 1 Etiology of portal vein thrombosis modified from Sobhonslidusk A[14] and Caronna[1]

From: The collateral caval shunt as an alternative to classical shunt procedures in patients with recurrent duodenal varices and extrahepatic portal vein thrombosis

Thrombophilic disorders

Local factors

Inherited disorders

Infections/inflammation

High risk of thrombosis (low prevalence):

Neonatal omphalitis

Antithrombin III deficit

Appendicitis

Protein C deficit

Diverticulitis

Protein S deficit

Pancreatitis

 

Cholecystitis

Low risk of thrombosis (high prevalence):

Perforated peptic ulcer

Leiden V factor mutation

Tuberculous lymphadenitis

Factor II mutation

 

Acquired disorders

Portal vein injury

Malignancy

Surgical shunts

Myeloproliferative disorders

Splenectomy

Use of oral contraceptives

Abdominal surgery

Antiphospholipid syndrome

Liver transplants

Pregnancy and postpartum

Blunt trauma

Paroxysmal nocturnal

 

Hemoglobinuria

 

Mixed disorders

Cancer of the abdominal organs Cirrhosis

Hyperhomocysteinemia