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Table 3 Frequencies of MTHFR C677T polymorphisms in childhood ALL patients and controls

From: Association of methylenetetrahytrofolate reductase (MTHFR) C677T and A1298C polymorphisms with the susceptibility of childhood acute lymphoblastic leukaemia (ALL) in Chinese population

MTHFR C677T Patient no. (%) Control no. (%) χ2 P OR (95%CI)
Genotype      
CC 28 (28.6) 29 (31.2)   - 1.00#
CT 44 (44.9) 49 (52.7) 0.046 0.829 0.930 (0.481 - 1.799)
TT 26 (26.5) 15 (16.1) 1.969 0.161 1.795 (0.790 - 4.079)
CT + TT 70 (71.4) 64 (68.8) 0.155 0.693 1.133 (0.609 - 2.106)
Allele      
C 100 (51.0) 107 (57.5)   - 1.00#
T 96 (49.0) 79 (42.5) 1.627 0.202 1.300 (0.868 - 1.947)
  1. #As reference group; OR, crude odds ratio; —, not applicable; CI, confidence interval. CC, CT and TT overall distribution test, χ2test = 3.109, P = 0.211.