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Figure 1 | European Journal of Medical Research

Figure 1

From: Glutamine synthetase mutations that cause glutamine deficiency: mechanistic insights from molecular dynamics simulations

Figure 1

Structure of human GS (PDB entry: 2QC8 [1]) in cartoon representation; (A) top view, (B) side view. Each subunit is colored differently. (C) Close up view of the active site of human GS with residues R324 (orange) and R341 (magenta), ADP (red), and GGP (blue) shown in sticks representation and three Mg2+ ions depicted as green spheres. The salt bridge between R324 and ADP is shown as a black dotted line.

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