Figure 4

The effects of benzodiazepines on GABA (gamma-aminobutyric acid) receptor and cholecystokinin (CCK) are shown. On one hand, binding of GABA molecules to their sites triggers the opening of a chloride ion-selective pore resulting in the hyperpolarization of the cell. On the other hand, benzodiazepines are likely to antagonize the CCK-induced neuronal activation.