Influence of IFN-β on the activity of osteoblasts and osteoclasts.
(a) IFN-β did not influence the AP activity of osteoblasts from osteoporotic and non-osteoporotic patients. (b) Osteoclasts of osteoporotic patients show a significantly increased TRAP-activity reducible by the stimulation with 100 ng/mL IFN-β. Bars represent mean ± sem, n = 12 osteoporosis group, n = 11 non-osteoporosis group. *** P <0.001 compared to the non-osteoporosis group, ° P <0.05, °° P <0.01, °°° P <0.001 compared to untreated cells.