Table 1 Baseline characteristics of subjects
Total sample | With DR | Without DR | P value | |
|---|---|---|---|---|
Demographic information | ||||
Number | 580 | 475 | 105 | - |
Age (year) | 64.73 ± 10.85 | 64.77 ± 10.96 | 64.54 ± 10.33 | 0.78 |
Sex (% female) | 362(62.31%) | 299(62.82%) | 63(60%) | 0.25 |
Height (cm) | 160.39 ± 8.80 | 160.37 ± 8.82 | 160.48 ± 8.77 | 0.88 |
Weight (kg) | 64.18 ± 10.64 | 64.25 ± 10.74 | 63.87 ± 10.19 | 0.64 |
SBP (mmHg) | 138.76 ± 20.90 | 138.21 ± 21.25 | 141.20 ± 19.12 | 0.06 |
DBP (mmHg) | 81.94 ± 11.51 | 81.94 ± 11.07 | 81.93 ± 13.31 | 0.99 |
Laboratory essays | ||||
FPG (mmol/l) | 8.69 ± 3.11 | 8.34 ± 2.75 | 10.28 ± 4.01 | <0.001 |
CP0 (ug/l) | 3.69 ± 2.13 | 3.71 ± 2.16 | 3.58 ± 1.98 | 0.40 |
PPG (mmol/l) | 14.76 ± 5.71 | 14.01 ± 5.37 | 18.13 ± 5.98 | <0.001 |
TC (mmol/l) | 5.36 ± 1.11 | 5.35 ± 1.09 | 5.37 ± 1.18 | 0.85 |
TG (mmol/l) | 1.97 ± 1.37 | 1.95 ± 1.36 | 2.04 ± 1.45 | 0.40 |
HbAlc (%) | 7.18 ± 1.57 | 6.97 ± 1.40 | 8.12 ± 1.92 | <0.001 |
BUN (mmol/l) | 6.10 ± 1.63 | 6.05 ± 1.53 | 6.34 ± 1.99 | 0.02 |
CR (μmol/l) | 67.39 ± 22.33 | 66.72 ± 20.05 | 70.43 ± 30.46 | 0.03 |
UA (mmol/l) | 0.29 ± 0.08 | 0.29 ± 0.08 | 0.28 ± 0.08 | 0.06 |
Medical history | ||||
Duration (year) | 7.38 ± 6.20 | 7.09 ± 6.13 | 8.67 ± 6.39 | 0.001 |
Age of onset year | 57.57 ± 10.79 | 57.91 ± 10.80 | 56.04 ± 10.62 | 0.02 |
KCNJ11 (rs5219 A%) | 231(40.51%) | 181(38.68%) | 50(49.01%) | 0.004 |