|
First author
|
Year
|
Country
|
Ethnicity
|
Polymorphisms
|
Number of cases
|
Number of controls
|
Method
|
HWE
|
|---|
|
Helmig
|
2010
|
Germany
|
European
|
TNF-α 308G/A
|
374
|
177
|
Real-time PCR
|
Yes
|
|
Flego
|
2009
|
Croatia
|
European
|
TNF-α 308G/A
|
230
|
230
|
PCR-RFLP
|
Yes
|
|
Stankovic
|
2009
|
Serbia
|
European
|
TNF-α 308G/A
|
70
|
102
|
PCR-RFLP
|
Yes
|
|
Colakogullari
|
2008
|
Turkey
|
European
|
TNF-α 308G/A IL-6 174G/C
|
44
|
59
|
PCR-SSP
|
Yes
|
|
Vogel
|
2008
|
Denmark
|
European
|
IL-6 174G/C
|
403
|
744
|
PCR
|
Yes
|
|
Seifart
|
2006
|
Germany
|
European
|
TNF-α 308G/A IL-6 174G/C
|
117
|
243
|
PCR-RFLP
|
Yes
|
|
Shih
|
2006
|
China
|
Asian
|
TNF-α 308G/A
|
202
|
205
|
PCR-RFLP
|
Yes
|
|
Campa
|
2004
|
Norway
|
European
|
IL-6 174G/C
|
250
|
214
|
Taqman
|
Yes
|
- TNF: tumor necrosis factor; IL: interleukin; PCR: polymerase chain reaction; PCR-RFLP: polymerase chain reaction-restriction fragment length polymorphism; PCR-SSP: polymerase chain reaction-sequence specific primer; HWE: Hardy-Weinberg Equilibrium.
